Take the Midosuji Line to Daikokucho Station and use Exit 2; the shrine is right there at street level. The ground is flat and sandy, so it works well for wheelchair users or anyone with mobility concerns. You can also enter from the south side to reach Shikitsumatsu-no-miya Shrine, dedicated to Susanoo, while the main street entrance leads directly to the better-known Daikoku Shrine. Both occupy the same grounds.
At Daikoku Shrine, look for the komainu statues featuring mice holding lucky mallets. Mice are considered messengers of Daikoku-sama here, making these a genuinely rare sight.